ODCs

Click node...

2 OMIM references -
1 associated gene
10 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
8 signs/symptoms

Fibronectin glomerulopathy

Dilated cardiomyopathy - hypergonadotropic hypogonadism


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	FN1	(0.63)	LMNA

Citations in the biomedical literature:

Fibronectin glomerulopathy		Dilated cardiomyopathy - hypergonadotropic hypogonadism
	Synonym(s): - GFND - Glomerulopathy with fibronectin deposits		Synonym(s): - Cardiogenital syndrome - Malouf syndrome - Najjar syndrome

	Classification (Orphanet): - Rare genetic disease - Rare renal disease		Classification (Orphanet): - Rare cardiac disease - Rare endocrine disease - Rare genetic disease - Rare infertility

	Classification (ICD10): - Diseases of the genitourinary system -		Classification (ICD10): (no data available)

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references

Fibronectin glomerulopathy		Dilated cardiomyopathy - hypergonadotropic hypogonadism
	Very frequent - Autosomal dominant inheritance - Chronic arterial hypertension - Edema of the legs / lower limbs - Functional anomalies of the kidney and the urinary tract - Hematuria / microhematuria - Nephrotic syndrome - Proteinuria - Renal failure - Renal glomerular defect / glomerulopathy Occasional - Intracranial / cerebral / meningeal hemorrhage		Very frequent - Abnormal / polycystic ovaries - Autosomal recessive inheritance - Broad nose / nasal bridge - Cardiomyopathy / hypertrophic / dilated - Decreased body hair / axillar / pubic hairlessness - Late puberty / hypogonadism / hypogenitalism - Precocious puberty - Ptosis